G418 Sulfate, Powder
C20H40N4O10 • 2H2SO4
Shipping conditions: Ambient
G418, also known as geneticin, is an aminoglycoside antibiotic similar in structure to gentamicin B1 used for selection and maintenance of prokaryotic and eukaryotic cells. It acts by blocking polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 µg/mL or less while animal cells may require 300-500 µg/mL.
Research or further manufacturing use only, not for food or drug use.